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Following the first CNS Anticancer Drug Discovery and Development Conference, the speakers from the first 4 sessions and organizers of the conference created this White Paper hoping to stimulate.
Here’s a really interesting paper from consultants Jack Scannell and Jim Bosley in PLoS ONE, on the productivity crisis in drug discovery. Several things distinguish it: for one, it’s not just another “whither the drug industry” think piece, of which we have plenty already.
The process of drug discovery and development ahs been greatly affected by investment in new technology and by governmental support of medical research. In most countries, the testing of therapeutic agents is now regulated by legislation and closely monitored by governmental agencies.
The pharmaceutical industry is facing unprecedented challenges owing to rising costs and the declining efficiency of drug research and development 1,2.As drug failures in clinical trials are primarily due to the poor predictive power of existing preclinical models, the drug discovery community has identified the critical need for new testing approaches to generate reliable predictions of drug.
As such, this Research Topic welcomes submissions from researchers in the field of computational drug discovery and design, including original research and review articles related to the in silico approaches used in Medicinal Chemistry.
Diversity of technology platforms.A striking feature of the vaccine development landscape for COVID-19 is the range of technology platforms being evaluated, including nucleic acid (DNA and RNA.
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